Construction of Conditional Acid Ceramidase Knockout Mice andin vivoEffects on Oocyte Development and Fertility
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چکیده
منابع مشابه
Construction of conditional acid ceramidase knockout mice and in vivo effects on oocyte development and fertility.
The number of resting follicles in the ovary and their successful maturation during development define the fertile female lifespan. Oocytes, enclosed within follicles, are subject to natural selection, and the majority will undergo apoptosis during prenatal life through adulthood. Our previous studies revealed high levels of the lipid hydrolase, acid ceramidase (AC), in human and mouse oocytes,...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2012
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000341453